The
Astrovirus
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Genera

Compiled by: Nick Knowles

Last updated: 06 March, 2013

Family: Astroviridae

Genus: Avastrovirus

Turkey astrovirus 1 (TAstV-1)
Virus Strain Region Length Accession No. Reference Comments
TAstV-1 ? CG

7003

Y15936

Jonassen et al., 1998;
Jonassen et al., unpub.
 
Turkey astrovirus 2 (TAstV-2)
Virus Strain Region Length Accession No. Reference Comments
TAstV-2 ? CG

7355

AF206663

Koci et al., 2000 associated with Poult Enteritis Mortality Syndrome
TAstV-2 USA: North Carolina (1988) ORF2(p) 785 AY320042 Guy et al., unpub.  
ORF1b(p) 723 AY320043 Guy et al., unpub.  
Turkey astrovirus 3 (TAstV-3)
Virus Strain Region Length Accession No. Reference Comments
TAstV-3   ORF 2 (capsid) 2514 AY769616 Tang et al., 2005  
Duck astrovirus 1 (DAstV-1) = DHV-2
Virus Strain Region Length

Accession No.

Reference Comments
DAstV-1 M52 ORF1b(p) 391 EU669003 Todd et al., 2009  
Duck astrovirus (DAstV) (probably DAstV-1)
Virus Strain Region Length

Accession No.

Reference Comments
DAstV C-NGB (China, 2008) CG 7722 FJ434664 Fu et al., 2009  
DAstV DA06 (China) CG 7722 FJ919225 Wang et al., unpub.  
DAstV DA07 (China) CG 7722 FJ919226 Wang et al., unpub.  
DAstV DA08 (China) CG 7722 FJ919227 Wang et al., unpub.  
DAstV DA93 (China) CG 7722 FJ919228 Wang et al., unpub.  
Duck hepatitis virus 3 (DHV-3)
Virus Strain Region Length

Accession No.

Reference Comments
DHV-3 X1222A Calnek ORF1b(p) 391 EU669004 Todd et al., 2009
Chicken astrovirus (CAstV)
Virus Strain Region Length

Accession No.

Reference Comments
CAstV-1 612 (SA, 1994) ORF1b(p) 391 EU669001 Todd et al., 2009  
CAstV-1 P22 18.8.00 (NET, 2004) ORF1b(p) 390 EU669000 Todd et al., 2009  
CAstV-2 FP3 (UK, 1984) ORF1b(p) 391 EU668999 Todd et al., 2009  
CAstV-2 11672 (UK, 09/01/2004) ORF1b(p) 391 EU668998 Todd et al., 2009  
CAstV-? MO-SEP-A799-05 ORF1b(p) 516 DQ324850 Pantin-Jackwood et al., 2006  
CAstV-? GA2011 (USA, 2007) CG 7539 JF414802 Kang et al., 2012  
CAstV-? 4175/GA/US/2006 CG 7008 JF832365 Cheng et al., unpub.  
Avian nephritis virus 1 (ANV-1)
Virus Strain Region Length Accession No. Reference Comments
ANV-1 G-4260 CG

6927

AB033998

Imada et al., 2000
ANV-1 EF91-276 (UK, 1984) ORF1b(p) 388 EU669002 Todd et al., 2009  
ANV-1 Sichuan/China/2009 CG 6941 HM029238 Zhao et al., 2011  
Avian nephritis virus 2 (ANV-2)
Virus Strain Region Length Accession No. Reference Comments
ANV-2 ? ORF 2 (capsid)

2536

AB046864

Imada et al., unpublished
Avian nephritis virus 3 (ANV-3)
Virus Strain Region Length Accession No. Reference Comments
ANV-3 19 (Netherlands) ORF1a(p)

407

FJ940720 de Wit et al., 2011
CG = complete genome; (p) = partial gene sequence

References

Carter, M.J., Willcocks, M.M., Kurtz, J.B. and Lee, T. The sequence of human astrovirus serotype 8. Unpublished.

de Wit, J.J., van de Laar, J.M.A.M., Biermann, Y., Verstegen, I., Edens, F. and Schrier, C.C. Unexpected virological results from chickens and turkeys with enteric and locomotion disorders. Unpublished.

Fu, Y., Pan, M., Wang, X., Xu, Y., Xie, X., Knowles, N.J., Yang, H. and Zhang, D. (2009). Complete sequence of a duck astrovirus associated with fatal hepatitis in ducklings. J. Gen. Virol. 90: 1104-1108.

Guy, J.S., Miles, A., Smith, L.G., Fuller, F. and Schultz-Cherry, S. Antigenic and genomic characterization of Turkey enterovirus-like virus (North Carolina, 1988 isolate) identifies the virus as Turkey astrovirus 2. Unpublished. [College of Vet. Med., North Carolina State Univ., 4700 Hillsborough St., Raleigh, NC 27606, USA]

Imada, T., Yamaguchi, S., Mase, M., Tsukamoto, K., Kubo, M. and Morooka, A. (2000). Avian nephritis virus (ANV) as a new member of the family Astroviridae and construction of infectious ANV cDNA. J. Virol. 74: 8487-8493.

Imada, T., Yamaguchi, S., Mase, M. and Tsukamoto, K. ORF 2 of avian nephritis virus serotype 2 (astrovirus). Unpublished. [Tadao Imada, National Institute of Animal Health, Department of Virology, 3-1-1, Kannondai, Tsukuba, Ibaraki 305-0856, Japan. (E-mail: imadatad@niah.affrc.go.jp, URL: http://ss.niah.affrc.go.jp/NIAH/hoge-s.html, Tel: 81-298-38-7760, Fax:81-298-38-7760)]

Jiang, B., Monroe, S.S., Koonin, E.V., Stine, S.E. and Glass R.I. (1993) RNA sequence of astrovirus: distinctive genomic organization and a putative retrovirus-like ribosomal frameshifting signal that directs the viral replicase synthesis. Proc. Natl. Acad. Sci. U.S.A. 90: 10539-10543.

Jonassen, C.M., Jonassen, T.Ø. and Grinde, B. (1998). A common RNA motif in the 3' end of the genomes of astroviruses, avian infectious bronchitis virus and an equine rhinovirus. J. Gen. Virol. 79: 715-718.

Jonassen, C.M., Jonassen, T., Saif, Y., Snodgrass, D., Ushijima, H., Shimizu, M. and Grinde, B. Comparison of capsid sequences from human and animal astroviruses. Unpublished.

Kang K.I., Icard A.H., Linnemann E., Sellers H.S. and Mundt E. (2012). Determination of the full length sequence of a chicken astrovirus suggests a different replication mechanism. Virus Genes 44: 45-50.

Koci, M.D., Seal, B.S. and Schultz-Cherry, S. (2000). Molecular characterization of an avian astrovirus. J. Virol. 74: 6173-6177.

Lewis, T.L., Greenberg, H.B., Herrmann, J.E., Smith, L.S. and Matsui, S.M. (1994). Analysis of astrovirus serotype 1 RNA, identification of the viral RNA-dependent RNA polymerase motif, and expression of a viral structural protein. J. Virol. 68: 77-83.

Major, M.E., Eglin, R.P. and Easton, A.J. (1992). 3' terminal nucleotide sequence of human astrovirus type 1 and routine detection of astrovirus nucleic acid and antigens. J. Virol. Methods 39:217-225.

Matsui S.M., Kim J.P., Greenberg H.B., Young L.M., Smith L.S., Lewis T.L., Herrmann J.E., Blacklow N.R., Dupuis K. and Reyes G.R. (1993). Cloning and characterization of human astrovirus immunoreactive epitopes. J. Virol. 67: 1712-1715.

Mendez-Toss, M., Romero-Guido, P., Munguia, M.E., Mendez, E. and Arias, C.F. Molecular analysis of a serotype 8 human astrovirus genome. Unpublished. [Genetica y Fisiologia Molecular, Instituto de Biotecnologia/UNAM, Av. Universidad 2001 Col. Chamilpa, Cuernavaca, Mor 62210, Mexico]

Mittelholzer, C., Hedlund, K.-O., Englund, L., Dietz, H.-H. and Svensson, L. (2003). Molecular characterization of a novel astrovirus associated with disease in mink. J. Gen. Virol. 84: 3087-3094.

Monceyron, C., Grinde, B. and Jonassen, T. (1997). Molecular characterization of the 3'-end of the astrovirus genome. Arch. Virol. 142: 699-706.

Monroe S.S., Stine S.E. and Glass R.I. Expression of the major capsid protein from human astrovirus type 5. Unpublished.

Monroe S.S., Jiang B., Stine S.E., Koopmans M. and Glass R.I. (1993). Subgenomic RNA sequence of human astrovirus supports classification of Astroviridae as a new family of RNA viruses. J. Virol. 67: 3611-3614.

Noel, J.S., Lee, T.W., Kurtz, J.B., Glass, R.I. and Monroe S.S. (1995). Typing of human astroviruses from clinical isolates by enzyme immunoassay and nucleotide sequencing. J. Clin. Microbiol. 33: 797-801.

Oishi, I., Yamazaki, K., Utagawa, E., Yamazaki, S., Inouye, S., Grohmann, G.s., Monroe, S.S., Stine, S.E., Ando, T. and Glass, R.I. (1994). A large outbreak of acute gastroenteritis associated with astrovirus among students and teachers in Osaka, Japan. J. Infect. Dis. 170: 439-443.

Oishi, I., Yamazaki, K., Kase, T., Kimoto, T., Sakon, N., Utagawa, E., Okuno, Y., Ando, T. and Glass, R. The clinical features and genomic sequence analysis of the causative agent, Katano virus of human astrovirus type 6, isolated from outbreak of gastroenteritis in Japan. Unpublished, [Osaka Prefectural Institute of Public Health, Laboratory of Pathology; Nakamichi 1-chome Higashinari-ku, Osaka 537-0025, Japan; E-mail: ooisi@iph.pref.osaka.jp; Tel:81-6-972-1321; Fax:81-6-972-2393]

Palombo, E.A. and Bishop R.F. Sequence analysis of astrovirus clinical isolates. Unpublished.

Pantin-Jackwood, M.J., Spackman, E. and Woolcock, P.R. (2006). Molecular characterization and typing of chicken and turkey astroviruses circulating in the United States: implications for diagnostics. Avian Dis. 50: 397-404.

Schreier, E. and Oh, D.I. Molecular characterization of human astrovirus serotype 3. Unpublished. [Molecular Virology, Robert Koch Institute, Nordufer 20, Berlin 13353, Germany]

Todd, D., Smyth, V.J., Ball, N.W., Donnelly, B.M., Wylie, M., Knowles, N.J. and Adair, B.M. (2009). Identification of chicken enterovirus-like viruses, duck hepatitis virus (DHV) type 2 and DHV type 3 as astroviruses. Avian Pathology 38: 21-29.

Wang, Q., Ushijima, H. and Shimizu, M. Genetic analysis of the capsid region of astroviruses. Unpublished. [Hiroshi Ushijima, Graduate School of Medicine, The University of Medicine, Department of Developmental Medical Sciences; Hongo 7-3-1,Bunkyo-ku, Tokyo 113-0033, Japan (E-mail: ushijima@m.u-tokyo.ac.jp, Tel:+81-3-5841-3629, Fax:+81-3-5841-3629)]

Willcocks M.M. and Carter M.J. (1992). The 3' terminal sequence of a human astrovirus. Arch. Virol. 124: 279-289.

Willcocks M.M. and Carter M.J. (1993). Identification and sequence determination of the capsid protein gene of human astrovirus serotype 1. FEMS Microbiol. Lett. 114: 1-7.

Willcocks M.M. and Carter M.J. The structural protein of a human astrovirus serotype 4. Unpublished.

Wilcocks, M.M., Carter, M.J. and Harbour D.A. Feline astrovirus capsid sequence and relatedness to human strains. Unpublished.

Willcocks M.M., Carter M.J., Silcock J.G. and Madeley C.R. (1991). A dot-blot hybridisation procedure for the detection of astrovirus in stool samples. Epidemiol. Infect. 107: 405-410.

Willcocks M.M., Brown T.O.K., Maddey C.R. and Carter M.J. (1994a). The complete sequence of a Human Astrovirus. J. Gen. Virol. 75: 1785-1788.

Willcocks M.M., Kurtz J.B., Lee T.W. and Carter M.J. (1994b). Prevalence of human astrovirus serotype 4: capsid protein sequence and comparison with other strains. Epidemiol. Infect. 0:0-0.

Zhao, W., Hua, X.G., Yuan, C.L., Cui, L., Shan, T.L., Dai, X.Q., Zhu, A.L., Yu, Y., Zhu, C.X. and Yang, Z.B. (2011). Sequence analyses of the representative Chinese-prevalent strain of avian nephritis virus in healthy chicken flocks. Avian Dis. 55: 65-69.


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